What's a knot -- and what's not -- in genomic mapping

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Genome mapping complements DNA sequencing, offering insight into huge, intact molecules between 150,000 and 1 million base pairs in length. Obtaining measurements of such large segments is not without its challenges, but new research into the physics of nanochannel mapping may help overcome a (literal) knot in the process and advance genome mapping technology. What's a knot -- and what's not -- in genomic mapping